Sentence examples for molecular mass difference from inspiring English sources

Since HGSNAT is predicted to have 5 potential N-linked glycosylation sites each potentially contributing ∼2 kDa to the size of the mature enzyme [11], this molecular mass difference was consistent with the hypothesis that inactive mutants lacked proper glycosylation.

Allele-specific H19 and Igf2 RNA gene expression analysis was based on SNPs between of inbred 129S1 (129) and CAST/Ei (CS) mouse strains and was analyzed by reverse-transcription PCR SNuPE assays [44], [47], except mass spectrometry quantified the extension primers (EP) based on molecular mass difference between alleles [48], [49].

We consider this an unlikely explanation of the molecular mass difference.

We conclude that in HEK293 cells propeptide cleavage does not occur resulting in the observed molecular mass difference to the native protein, which accounts for the propeptide fragment.

According to the molecular mass difference of the full-length and the shed forms of COL-99 (Fig.  6b) and the PrOP 1.0 scores of predicted furin cleavage sites, COL-99 can potentially be shed by furin cleavage at RRVR/RKMR and RRKR, resulting in an ectodomain composed of 544 or 495 amino acids starting from N or A, respectively, to R (Additional file 1 and Fig.  6b).

The slight molecular mass differences (about 5 Da) between rHLZ and commercial HLZ was detected (Table 2).

The small molecular mass differences between the predicted and MALDI-TOF and MS/MS observed for native TRP47 (179 Da) and TRP32 (288 Da) suggest that the mass of the modifications is consistent with two or three phosphates outside the TR region, and confirmed that the abnormally migrating TR region is not modified by glycans or phosphate.

Nevertheless, we did find molecular mass differences among flagellins produced by clinical isolates.

However, such IHC studies alone are unable to provide any information regarding PrP glycosylation or molecular mass differences.

About the typing technique used, it is important to note that the apparent molecular mass differences can be useful but present as rather imprecise and impractical criteria for molecular typing of PrPres (Fig. 3).

This formulation of the problem is not easily accessible by algorithmic means; to this end, we use an alternative formulation which, for additive scorings, is equivalent to the above [34]: for each peak in the fragmentation spectrum, we find all molecular formulas with mass difference sufficiently small.