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The similarity between the concatenated tree and concordance trees indicates that a robust phylogenetic topological structure could be predicted based on hundreds of molecular loci, even though these had markedly divergent rates of molecular evolution.
As morphological characters are not helpful here, a more detailed molecular study comprising more numerous Oscarella species and more molecular loci is needed to resolve this issue.
Certain molecular loci may be present difficulties in case the genetic diversity is significantly lower in a specific lineage than average, then failing to distinguish closely related but genetically isolated lineages.
However, also in that case the method is very helpful in recognising critical groups which are in need of additional taxonomic investigations, and the MRI may well be used to compare the suitability of distinct molecular loci sequenced from the same organisms for molecular taxonomy.
Additional file 1: Phylogenetic relationships among the Ranunculales as evidenced by molecular loci and morphological data.
(PDF 854 kb) Additional file 2: Phylogenetic relationships among the Ranunculales as evidenced by molecular loci and morphological data.
Similar(34)
Our data significantly inform this debate by clearly establishing the primary molecular locus that causes differential Glo1 expression among mice and by providing extensive support for a positive correlation between Glo1 expression and anxiety-like behavior.
While our ignorance is profound--the precise molecular locus of the antitumor expression of the anthracyclines remains unknown--there is now evidence that the relationship of the anthracyclines to the DNA (possibly requiring enzymatic cooperation) and to the membranes, with neither event requiring redox chemistry, may comprise the core of the antitumor effects.
Partial DNA profiles are often obtained from degraded forensic samples due to allelic and locus dropout, particularly at the high molecular weight loci.
These molecular marker loci showed highly significant allele frequency differences between stress-selected (SS) and non-stress selected (NS) sets of F2 3 lines derived from Apo/IR64 cross.
This article has identified common molecular sequence structure loci that potentially contribute toward both manufacturability and safety profiles of the therapeutic antibodies, thereby laying a foundation for simultaneous optimization of these attributes in novel and follow-on candidates.
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