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Analysis of aberrations at the molecular level found in each patient's tumor cells can identify new therapeutic options.
Further investigation at the molecular level found that collagen type II (col2a1), a chondrocyte differentiation marker, was downregulated in pax1b morphants), suggesting that chondrocytes differentiation was affected in pax1b morphants.
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Subsequent to this study, several parasitic relatives of dinoflagellates, such as Syndinium, Hematodinium and Amoebophrya, were characterized at the molecular level and found to belong to Marine Alveolate Clade II; Dubosquella, Ichthyodinium and the so called 'RP parasites' were found to belong to Marine Alveolate Clade I [5] [9].
At the molecular level, we found that LSD1 regulates osteogenesis-associated genes expression through its histone demethylase activity.
At the molecular level, we found that although IPCs had a similar distribution of membrane proteins to normal pancreatic beta cells, they still could not mimic the physiological regulation of insulin secretion performed by normal pancreatic beta cells.
At the molecular level, we found that free Brk1 is an homotrimer based on SEC analysis, cross-linking and association of three different forms of Brk1.
At the molecular level, we found indications that Hsp90b1 and Hspa5 were coregulated during the transition from egg to embryo but Hspa5 could not compensate for the lack of Hsp90b1.
At the molecular level, we found increases in glycogen accumulation, gene induction of ANF and increased collagen contents, which are all linked to the development of cardiac hypertrophy and failure [22].
To test whether resveratrol and glutathione are formaldehyde scavengers, at the molecular level, we found that resveratrol and glutathione brought about chemical deactivation of formaldehyde in vitro (Fig. 6B).
At the molecular level, we found that the organization of stable MTs were affected in futschN94/+ TBPHD23/TBPHD23; elav-GAL4>TBPH flies (Figure 5Ax xii) compared to +/+; TBPHD23/TBPHD23; elav-GAL4>TBPH flies (Figure 5Avii ix), indicating that TBPH function may requires futsch activity to stabilize MTs during synaptic growth and bouton formation.
At the molecular level we found that both p19ARF and p16 were progressively up regulated during passages (with respect to the spontaneous level of MEF p0) (Fig. 1B).
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