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The ESI-TOF-MS/MS of these molecular ions generated prominent daughter ions from the loss of water and HNE.
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Loss of a neutral ethane molecule from quasi-molecular ion generates first daughter ion with m/z 177 which corresponds to [M + H – C2H6] = [C11H13O2]; further fragmentation of first daughter ion and elimination of a neutral C = O molecule generates a stable ion which corresponds to base peak at m/z 149 [M + H – C2H6 - CO] = [C10H13O].
HRMS was obtained Micromass Q-Tof Ultima mass spectrometer and [ M+H]+ molecular ions were generated by electrospray ionization.
Hankin et al. showed within a singular class of lipids and for similar tissue types that the intensity of lipid molecular ion signals, generated in positive-ion MALDI MSI experiments, does in fact relate to the quantity of molecules in a tissue sample [ 87].
Using molecular oxygen as a substrate, the production of H2O2 by synthetic Aβ depends on Fe2+ ions generated via a redox cycling of iron (Huang et al., 1999a; Khan et al., 2006).
Ions generated from the ESI source were transferred into the ICR (ion cyclotron resonance) cell through ion transfer lenses.
These primary particles are typically elemental ions generated from a liquid metal ion source.
The measurement of ions generated after negative chemical ionization was performed in selective ion mode.
Further fragmentation of molecular ion species generates product ions that provide structural information for the compound of interest and can inform the development of sensitive quantitative assays.
The electrons can react with molecular oxygen to produce superoxide radical (( {O}_2^{cdotp -} )) through a reductive process, whereas the holes can abstract electrons from water and/or hydroxyl ions generating hydroxyl radicals (OH·) through an oxidative process [18 20].
Peaks of tanshinones could be recognized by their generated molecular ions of [M+Na]+ and [M+H]+ while peaks of salvianolic acids were easily generated their molecular ions of [M−H]−.
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