Investigators intensively evaluate well-established oncogenes or chromosome aberrations, using large tumor repositories, in an effort to widen their knowledge on the molecular mechanisms, gene interrelationships or gene function underlying breast cancer.
This provided us with the opportunity to gain invaluable insights into the molecular mechanisms underlying the interrelationships among energy metabolism, behavioral, and life-history traits that have evolved in natural populations.
MetaCore identifies networks based on a manually curated database containing known molecular interactions, functions, and disease interrelationships.
In general, our inferred chloroplast phylogenies are very similar to recently published molecular trees, in which the interrelationships and the monophyly of magnoliids, monocots and eudicots were strongly supported [ 9, 10, 47, 48].
52, 53 The interrelationship between these molecular targets suggests the expression and action of PRRs are the primary effector molecules in a downstream cascade that initiate dysregulation of insulin homeostasis.
To characterize the interrelationship between the molecular markers investigated in this study, we performed confocal immunofluorescence microscopy colocalization experiments of c-met with Sdc1 and E-cad in human breast cancer cell lines.
Interrelationships among dinoflagellates in molecular phylogenies are largely unresolved, especially in the deepest branches.
Biomarker discovery and specific molecular recognition tools may unravel the interrelationships amongst Aβ assemblies and facilitate detection and characterization of these assemblies early in the course of AD.
Importantly, the identified molecular network was found to contain complex interrelationships, providing further insight into epilepsy's underlying pathology.
Second, all the cellular and molecular state variables are identified and the interrelationships (transitions) between them determined.
