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In contrast to the cascade of molecular interactions required for cell entry from blood into tissues [35] [37], the multistep requirements for lymphocyte egress, in particular for Treg cells, have not been defined.
The basic molecular interactions required for the signal transduction function of the plasma membrane can be fundamentally understood and conveniently summarized as the cooperative actions of these mesoscale domains, where thermal fluctuations/movements of molecules and weak cooperativity play crucial roles.
This concept is consistent with molecular interactions required to explain the chemistry and location of cross-links in fibrils.
These studies reveal a conserved binding site found on the superfamily of MAPK kinases while providing insight into the molecular interactions required for YopJ inhibition.
The molecular interactions required to produce classes L1 and L2 are shown in File S2, Figure S39 and Figure S40.
Bacterial transmission in novel species suggests absence of very tight specificity in the molecular interactions required, or considerable evolutionary conservation of the host molecules exploited.
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Investigating chemical and material problems at an atomistic scale through capturing and understanding molecular interactions requires effective implementation of molecular modeling or computational chemistry techniques.
Thus, we suggest that prelamin A accumulation in MADA interferes with both heterochromatin organization and a variety of inter-molecular interactions required for proper nuclear envelope assembly.
A complex repertoire of intracellular and extracellular molecular interactions are required for collagen IV secretion and supramolecular assembly into BMs.
But both considerable computer power and many biological details (e.g., rate and equilibrium constants for all or most of the molecular interactions) are required for the informative use of such methods.
Studies of WRN-deficient cell lines have provided evidence for a role of WRN in the response to replicational stress through a recombinational repair pathway [ 1, 2]; however, the precise molecular functions and protein interactions required for WRN to help cells proliferate, maintain genomic stability, and deal with endogenous or exogenously induced DNA damage are not well understood.
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cell interactions required
molecular changes required
molecular carriers required
molecular players required
molecular features required
molecular adaptations required
molecular processes required
molecular components required
molecular factors required
molecular signals required
molecular resources required
molecular structures required
molecular mechanisms required
molecular switches required
molecular tools required
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