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Instead, they appear to rely on the weak molecular interactions known as Van der Waals forces for their staying power.
The most intensively investigated mechanism is the ability of the GR to inhibit the activity of other transcription factors through molecular interactions known as tethering.
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Our models incorporate all individual molecular species and interactions known to be involved in the transcription, translation, regulation, and induction steps in the tetracycline-regulated expression system.
The C-peptide of proinsulin exhibits multiple activities and several of the underlying molecular interactions are known.
The results showed that LdUba5 protein can be precipitated with all three forms of LdUfm1 indicated by the specific ∼43 kDa band in all the transfectants except in untransfected Leishmania cells that do not express Ha-tagged Ufm1 (Figure 1E) even though such molecular interactions are known to be transient in other Ubls.
Finally, we examined whether genetic interaction exists between TNFAIP3 and TNIP1 SNPs, because molecular interaction is known between the protein products of these genes.
The molecular basis of diseases can also be explored using the interactome, a network created by integrating all interactions known to occur between proteins.
Molecular interactions, however, are known to show a switch-like behavior, which can be modeled using sigmoid shaped Hill functions [ 15] (see Additional data file 2).
This web-based entry tool allows for the mapping of gene expression data into relevant pathways based on their functional annotation and known molecular interactions [23] [25].
IPA software integrates expression changes with known molecular interactions and disease processes [ 19].
Most of the gene products are connected; i.e., could be linked functionally by way of known molecular interactions.
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