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The number of nitrogen atoms present in the head group can contribute to the growth of micellar structure due to changes in molecular interactions based on the degree of protonation.
The tool "Path Explorer" was used to search for documented molecular interactions based on the Ingenuity® Knowledge Base.
We manually constructed a map of Alzheimer's disease signaling networks by assembling molecular interactions based on published papers using the modeling software, CellDesigner ver. 4.2 (http://celldesigner.org/).org/
Networks of direct and indirect molecular interactions based on the whole-genome expression data were identified and visualized using the Ingenuity Pathway Analysis http://www.ingenuity.com.com
We have developed both a merging algorithm and a scoring system for molecular interactions based on the proteomics standard initiative molecular interaction standards.
Tethering proteins to solid surfaces is fundamental for the development of biochips and optical biosensors for high-throughput analysis of molecular interactions based on surface plasmon resonance and bio-layer interferometry.
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We started with a baseline model and expanded it systematically to include a specific transport process or molecular interaction, based on experimental observations and hypotheses.
Successive inter- and intra-molecular interactions based on the rules of Watson Crick base pairing allow us to design self-assembling molecular systems with predictable folding pathways and conformational changes.
Conformation-sensitive UIC2 could identify different classes of drug modulators of P-glycoprotein and the molecular mechanism underlying their interactions based on mutations in the multidrug resistance gene (MDR1; ABCB1) which led to different conformations of the molecule [21], [22].
In contrast, for cooperative interactions, we support annotation of molecular interaction mechanisms based on inference from a combination of different experimental approaches described in a single publication or even assembled by curators based on multiple publications.
Parodi had managed to convince her of the future importance of molecular interaction maps based on the work of his close friend Kurt Kohn at the National Cancer Institute in the United States.
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