These novel functions have broadened our understanding of the signalling pathways and molecular intermediates interacting with AhR under both homeostatic and pathological conditions.
Recent years have witnessed remarkable advances achieved using these techniques, including the generation of a detailed histone DNA energy landscape, elucidation of nucleosome disassembly processes, and real-time monitoring of molecular motors interacting with nucleosomes.
In an effort to mimic viral infection capabilities during non-viral gene delivery, a modular recombinant protein named T-Rp3 was recently developed, containing a DNA binding domain, a dynein molecular motor interacting domain, and a TAT-derived transduction domain.
Small G-proteins of the superfamily Ras function as molecular switches, interacting with different cellular partners according to their activation state.
An immune epitope is defined by the IEDB as the molecular structure interacting with receptors of the immune system (T cell and B cell/antibody).
In the era of modern vaccinology, adjuvants should have well-defined molecular targets, interacting with specific receptors on cells that have capacity to modulate the course, quality and intensity of the immune response.
The actin associated protein, palladin, is a critical structural component of the actin cytoskeleton, and functions as a molecular scaffold interacting with multiple proteins in the actin cytoskeleton [21], [24], [39], [40], [41], [42].
10.7554/eLife.04000.036 Figure 8. Model for molecular pathways interacting to control the patterning of the nephron.
Biopython includes modules for reading and writing different sequence file formats and multiple sequence alignments, dealing with 3D macro molecular structures, interacting with common tools such as BLAST, ClustalW and EMBOSS, accessing key online databases, as well as providing numerical methods for statistical learning.
