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Testing for hrHPV DNA with new molecular instruments has excellent performance and reproducibility.
These engineering efforts yielded a next-generation DNA HCR in situ amplification technology that dramatically improves on the performance, cost, and durability of the first-generation RNA technology, providing biologists with superior programmable molecular instruments for mapping the state of endogenous biological circuitry within intact organisms.
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This chapter will also touch on the available molecular diagnostic instruments and the design of a clinical molecular laboratory.
Compared with other common in-field applied molecular spectrometry instruments, the inherent high selectivity and multi-element applicability of FAFS highlighted the superiority and potential of the proposed analytical system.
However, development of the molecular 'surgical instruments' to break and rejoin DNA strands at sequences of our choice and thus bring about desired genetic rearrangements is still at a primitive stage [1], [2].
Additionally, although a number of molecular imaging instruments are available, all have their limitations.
Further studies are necessary to identify additional serum biomarkers that can be integrated with modern molecular imaging instruments.
Dynamic light scattering (DLS) experiments were performed on a DynaPro Molecular Sizing Instrument (Protein Solutions).
DLS was performed at 650 nm at 20°C or 37°C with a DynaPro-E-20-660 molecular sizing instrument (Protein Solutions; Wyatt Technologies, Santa Barbara, CA, USA).
The size of liposomes in individual SSL batches was tested by photon correlation spectroscopy using a DynaPro-801 molecular sizing instrument equipped with a temperature-controlled microsampler (Protein Solutions, Charlotteville, SC, USA).
The detection performance of this, relative to other MS methodology, is related to aspects of molecular separations, instrument duty cycle, and signal recognition, topics that are broadly involved in MS analyses.
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