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Those last promising results encouraged our group to initiate this prospective pilot study by evaluating whether molecular imaging utilizing 99mTc-sestamibi SPECT/CT could reliably differentiate between oncocytomas and RCCs.
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Ultrasound-based molecular imaging utilizes acoustically active particles (contrast agents) bearing targeting ligands that specifically bind to a molecule of interest.
FDG-PET utilizes molecular imaging to obtain images, not of the morphology, but of the metabolism of cells.
Indeed, both in vitro nanosensors and in vivo nano-molecular imaging will be utilized to accomplish our long-term goals.
Molecular imaging aims to extend current clinical imaging approaches by utilizing targeted agents to illuminate important biology in living subjects.
An alternative molecular imaging approach is breast-specific gamma imaging (BSGI), which utilizes 99mTc-sestamibi.
See images of the VisEn molecular imaging system being used on mice.
Together these results demonstrate the capabilities and advantages of a new, more stable, nanometer-scale ultrasound contrast agent that can be utilized in future work for diagnostic scans and molecular imaging.
Our results show that hexagonal NaGdF4 Eu3+ nanoparticles are excellent candidates for applications that utilize X-ray activated luminescence and could have a future role for in vivo molecular imaging studies.
Biopolymers for molecular imaging.
S.B., N.S. provided molecular imaging agent support.
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