Sentence examples for molecular imaging tracers from inspiring English sources

By using different molecular imaging tracers, we begin to appreciate the heterogeneity of metastatic disease within individual patients.

CD13 is selectively upregulated in angiogenic active endothelium and can serve as a target for molecular imaging tracers to non-invasively visualise angiogenesis in vivo.

The preclinical data presented are compelling, and it is evident that antibody-based molecular imaging tracers will play an important future role in the diagnosis and management of cancer and other diseases.

Integrin αv β3 targeting molecular imaging tracers consist of two functional domains, a targeting moiety with affinity to integrin αv β3 and a signaling component such as a radioisotope, fluorophore, or microbubble.

In the past decade, the efficacy of several RGD-containing molecular imaging tracers monitored and tumor integrin αv β3 expression has been evaluated using single photon emission computed tomography, positron emission tomography, magnetic resonance imaging (MR), optical imaging, and ultrasonography imaging [ 6].

We have recently developed a molecular imaging tracer for imaging VEGFRs known as scVEGF/99mTc; an engineered single-chain (sc) form of VEGF radiolabeled with technetium Tc 99m (99mTc).

Valid imaging targets for molecular imaging tracer development are membrane-bound hypoxia-related proteins, expressed when tumor growth outpaces neo-angiogenesis.

A molecular imaging tracer, [C]-Pittsburgh compound B (PiB), which binds to Aβ plaques, has been used in small-animal and human PET (positron-emission tomography) imaging studies to monitor Aβ plaque load and its clearance in response to treatment [ 22].

The first clinical trial with a Ga-labeled anti-HER2 nanobody as a molecular imaging tracer targeting the breast cancer marker HER2 is being finalized (EudraCT 2012-001135-31) and will generate the first in-human data on tolerability, dosimetry and its capacity to identify HER2 overexpressing lesions.

Molecular imaging with targeted tracers might increase specificity and sensitivity of detection.

Molecular imaging with targeted tracers by positron emission tomography (PET) allows for the noninvasive detection and characterization of biological changes at the molecular level, leading to earlier disease detection, objective monitoring of therapies, and better prognostication of cardiovascular diseases progression.