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Taking into account sensitivity, spatial resolution, and temporal depth resolution, each molecular imaging tool has different sets of capabilities [6].
Positron emission tomography (PET) is a non-invasive molecular imaging tool for quantitative analysis of in vivo physiology.
The probe YB could use as a significant molecular imaging tool to study the endogenous GSH in living cell and a practical detector for H2S in the papermaking wastewater.
Although CT imaging is not commonly used as a molecular imaging tool in clinical practice because of the fine performance in high spatial resolution and short acquisition time, CT-relevant targeted and specific contrast agents were also rapidly developed recently, aiming to a strongly selective X-ray attenuation and corresponding enhanced contrast.
Therefore, this work demonstrates the translation of PT-OCT to in vivo imaging and represents the next step towards its use as an in vivo molecular imaging tool.
Basic physical sciences are however not driving the development of this technology; it is the biomedical applications that have animated the field, as DNP-enhanced C MRI has unique potential as a molecular imaging tool.
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With such a wide range of capabilities, molecular imaging tools should be combined to enhance overall image quality.
For practical purposes, molecular imaging tools are not sufficient by themselves due to their inherent limitations.
In the case of nuclear molecular imaging tools (PET and SPECT), radionuclide-labeled substances are used as contrast agents.
So far, more than 500 patients and volunteers in Europe, Asia, and Australia have been investigated using these novel molecular imaging tools.
This work has led to clever design of molecular imaging tools and many contributions to studies of brain function in animal models.
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