Molecular imaging agents are useful for imaging molecular processes in living systems in order to elucidate the function of molecular mediators in health and disease.
Several ligands were developed as molecular imaging agents of PS.
Absorbed radiation doses in primary target organs, compared for 64Cu-MM-302 and approved molecular imaging agents.
Ultrasound-mediated, transient blood-brain barrier disruption allows the delivery of both therapeutic and molecular imaging agents in Alzheimer's mouse models, which should aid pre-clinical drug screening and imaging probe development.
Many more molecular imaging agents should be evaluated in cancer patients, as F-FDG is certainly not sufficient for melanoma detection, staging, and treatment monitoring.
Photoacoustic imaging uses light pulses to excite molecular imaging agents, causing thermal expansion that produces ultrasound waves recorded by an ultrasound transducer (Yang et al., 2012).
Molecular imaging agents play a major role in drug discovery and development because of their ability to quantify drug properties in vivo.
Although an incomplete list, those entities were chosen because they have all been imaged clinically, have all proved useful and provide models for the translation of experimental molecular imaging agents (Table 1).
A combination of optical imaging technologies with cancer-specific molecular imaging agents is a potentially powerful strategy to improve cancer detection and enable image-guided surgery.
Determination of lipophilicity and its use as a predictor of blood brain barrier penetration of molecular imaging agents.
My research is focused on developing and evaluating molecular imaging agents for visualizing neurological diseases in living subjects.
