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CircRNAs have a more stable molecular structure that can resist to exoribonuclease comparing to those linear ones, and their molecular functions include microRNA sponge, regulatory roles in transcription, mRNA traps that compete with linear splicing, templates for translation and possibly other presently unknown roles.
Other highly enriched molecular functions include chemokine and cytokine activity/receptor binding (8 of the top 15) and peptidase activities.
The top five main molecular functions include ion binding (28.5%), peptidase activity (11.8%), signal transducer activity (9.9%), enzyme regulator activity (7.5%) and oxidoreductase activity (5.9%).
Their overrepresented molecular functions include kinase, pyrophosphatase, and transferase activities as well as catalytic, molecular transducer, motor, and receptor activities (fig. 1 B).
The enriched biological processes and molecular functions include terms such as - "GO 0009414 - response to water deprivation", "GO 0015250 - water channel activity", and "GO 0009651 - response to salt stress", consistent with the experimental treatments (dehydration and salt stress).
Similar(55)
Similar UVR exposure can also affect key molecular functions including collagen fibril assembly and protease susceptibility [65, 68, 69].
The methylation PSF includes 48 methylated sites in 44 genes coding for basic molecular functions, including transcription regulation, DNA binding, cytokine, and transferase activity.
Gene Ontology (GO) analysis using GoSurfer revealed major categories for genes significantly altered by cocaine, which demonstrated changes in gene expression related to specific molecular functions, including angiogenesis, apoptosis and cell death, cell adhesion, neurogenesis and axon guidance.
That is, the molecular functions included an over-representation of transcriptional functions such as transcription factor regulation and DNA binding.
Over-represented molecular functions included ATP binding, nucleotide binding, lipoic acid binding, oxidoreductase and L-lactate dehydrogenase activity.
Similarly, over-represented molecular functions included actin-binding (GO 0003779), calcium ion binding (GO 0005509) and phospholipid binding (GO 0005543).
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molecular circuits include
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molecular phylogenies include
molecular circuitries include
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molecular orbitals include
molecular components include
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