Sentence examples for molecular functional effect from inspiring English sources

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The molecular functional effect of ERCC2 polymorphisms remains unclear.

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Genetic variants may have specific molecular functional effects that cumulatively build a complex clinical phenotype.

Understanding the molecular functional effects of mutants in myosinopathies is crucial to establish potential therapeutic strategies.

SNPs3D: SNPs3D is a Web site which assigns molecular functional effects of nonsynonymous SNPs based on structure and sequence analysis.

The molecular functional effects of non-synonymous SNPs based on sequence and structure analysis were retrieved from the SNPs3D web resource and database 36 for genes curated in the Comparative Toxicogenomics Database (CTD) 35 to have a relationship with arsenic.

We have now performed a detailed analysis of the molecular and functional effects of Sirt1 deficiency in the germ line of Sirt1 knock-out mice.

We have examined the molecular and functional effects of five different, but structurally related, nitrotoluenes on using an integrative systems biology approach to gain insight into common and disparate mechanisms underlying effects caused by these chemicals.

To address the many questions concerning the molecular and functional effects of rosiglitazone on the diabetic heart, we used CMR imaging and echocardiagraphic studies to assess the development of cardiomyopathy in untreated and rosiglitazone-treated db/db mice, as well as normal db/+ mice.

Here, we addressed the molecular and functional effects of IFN treatment on immune cell subsets of osteosarcoma patients, both in vivo and ex vivo.

We studied the molecular and functional effects of interferon treatment on peripheral blood lymphocytes and monocytes of osteosarcoma patients, both in vivo and ex vivo.

Finally, we used RPPM to study the molecular and functional effects of UCN-01 and demonstrated that the sensitivity to UCN-01 correlates with activation of survival signals mediated by PDK1 and the DNA damage response initiated by CHK1.

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