Because there may be several functional assignments for a given protein (i.e., based on a phenotypic assay, a biochemical assay, or a molecular function), there may be several synonyms for the protein name (and similarly, for the gene full name).
As for molecular function, there were 722 probe sets with GO term annotations and the significant GO terms were "glutathione transferase activity" (GO: 0004364, FDR 1.08E-24), "peroxidactivityvity" (GO: 0004601), and "oxygen binding" (GO: 0019825, majority P450 proteins).
For molecular function, there is an apparent enhancement of "molecular transducer activity" for N_F (Fig. 7).
Under molecular function, there are two enriched categories, "peroxidase function" and "calcium binding".
Similarly in the molecular function there is enrichment for electron carrier activity, oxidoreductase activity, and transporter activity, particularly ion transport.
Within molecular function, there were a total of 11 pathway categories at level 2 gene ontology with over 75% of the genes in two categories: binding (mean = 52.3%), and catalytic activity (mean = 24.3%; Figure 5b).
Finally, about the molecular functions, there are RNA binding, heparin binding and cyclin binding, which are very different from the late stage bladder cancer.
Finally, about the molecular functions, there are enzyme binding, protein binding and nucleotide binding, which are very different from the early stage bladder cancer.
As for the subsystem "molecular function" (MF), there is a significant higher functional similarity compared with random gene pairs (p-value = 0.007345), however this discrepancy was not found when compared with other adjacent gene pairs.
Within the molecular function category, there was a high percentage of genes with binding, catalytic activity, and transporter activity.
At the molecular function level, there were significantly more DEGs in catalytic activity and binding GO terms than in other terms.
