Considerable numbers of genes participate in molecular functions like protein tyrosine kinase activity and EGFR activity.
It also displays the involvement of genes in molecular functions like protein serine/threonine kinase activity and TGFBR activity.
Molecular functions like protein kinase and MAPK activities and EGFR activity have been found to be associated with significant number of genes from the sub-network.
GO terms associated with molecular functions like peroxidase, hydrolase, antioxidant, dioxigenase, electron carrier activity are enriched in sensitive genotypes.
miR156-miR160 coexisted in 110 unique genes and transcripts, enriched for molecular functions like RNA polymerase activity (P-value: 1.7E-03 1.7E-03
miR156-miR166 coexisted in 25 unique genes and 36 unique transcripts, where genes associated with molecular functions like Beta-Galactosidase activity (P-value: 1.6E-03 1.6E-03found enriched.
Further cellular and molecular functions like proliferation and apoptosis were significantly up- or downregulated by all TTP treatments but mostly by the 120 s dose.
While molecular functions like DNA binding activity retained highest number of 594 sequences followed by 513 sequences for catalytic activity in pigeonpea [ 62].
We found that among the up-regulated genes, 342 genes contained HBS within 10 Kb upstream sequence and they were enriched in molecular functions like RNA polymerase II transcription factor activity (GO 0003702), transcription factor activity, (GO 0003700) and biological processes like regulation of transcription (GO 0045449) (Additional file 6).
It is worthy of mentioning that some of these molecular functions like transcription factor activity, chromatin binding, sequence-specific DNA binding and biological processes like signal transduction, regulation of transcription, DNA-dependent, synaptic transmission were already predicted when we performed genome wide analysis of HBS containing genes (Table 1 and Additional file 2).
miR156-miR396 coexisted in 208 unique genes and 263 unique transcripts, showing enrichment for genes associated with molecular functions like Brassinosteriod-sulfotransferase activities (P-value: 4.9E-04), Fructokinactivitiesties (P-value: 7.3E-04), Glucokinactivitiesties (P-value: 7.3E-04) and UDP-gluco-4-aminobenzoate activities (p-value: 7.3E-04).
