In most other treatments categories, numbers of passing ESTs had proportional numbers of associated GO- Molecular Function terms; however, the SHE downregulated category, which had only 2 passing ESTs (dna replication licensing factor mcm7 and serine/threonine-protein kinase mph1), had 19 GO- Molecular Function terms.
Their detailed molecular function is still under debate; however, they influence a broad range of cellular processes, including translation, transcription and autophagy [ 24, 26, 27, 28].
SF21 belongs to a gene family expressed in pollen and pistil in angiosperms and the encoded protein is important for pollen-pistil interactions [ 80, 81]; however, the molecular function is still unknown.
The molecular function of Ctf4, however, remains unclear, and it is intriguing to address whether Ctf4 is implicated in modulating the level of histone acetylation.
Recent studies suggested that Prxs may eject also molecular chaperone functions; however, little is known about the precise mechanism of chaperone function and its physiological significance.
However, molecular function does not have a clear OPM equivalent.
However, molecular function of these long palindromes in insect mtDNA needs further analysis.
However, the molecular function of PVT-1 is still controversial.
Fibrosis, which entails excessive extracellular matrix (ECM) deposition and tissue remodeling by activated myofibroblasts, leads to loss of proper tissue architecture and organ function; however, the molecular mediators of myofibroblast activation have yet to be fully identified.
Appropriate regulation of HSC quiescence is thought to be crucial to maintain their lifelong function; however, the molecular pathways controlling stem cell quiescence remain poorly characterized.
