Both of these techniques are intended to find HSQC spectra matches that supplement information generated by established molecular fingerprint methods.
When we used a test set of 37,138 positive and 42,928 negative ligand-target interactions, among the five tested molecular fingerprint methods, at significance level 0.05, Topological-based model yielded the best precision rate (83.7 %) and ({F_{0.25}{textMeasure}) (0.784) while Atom pair-based model yielded the best (F_{0.5}{textMeasure) (0.694).
The identity of both isolates was determined by molecular fingerprinting methods.
Contaminated peat and sawdust have been associated with outbreaks of M. avium subsp. hominissuis infections in swine as confirmed by molecular fingerprinting methods [ 7, 9, 11, 14, 15].
Such molecular fingerprinting methods to compare strains can provide useful information about patterns of infection with S. maltophilia and possible sources and modes of transmission [ 5, 6].
Among these molecular fingerprinting methods, PCR-DGGE represents a rapid and reliable technique to identify the predominant microbiota in various ecological niches [ 38, 39].
Because the outbreak had substantial economic consequences to the manufacturer, it was important to get as strong evidence as possible about the source of these infections, also by using two types of molecular fingerprinting methods.
With the advent of new molecular techniques, we have been able to investigate bacterial diversity in different microhabitats using molecular fingerprinting methods and sequence analysis of microbial small subunit ribosomal (r) RNA genes (16S rRNA) and other universal targets (such as cpn60) [ 13, 36, 37].
The research aimed to investigate whether new approaches can improve a molecular fingerprint-based method of identifying structurally similar compounds from databases of HSQC spectra.
In this study, a molecular community fingerprinting method was used to monitor the putative establishment and colonization of allochthonous consortia in resident multi-species biofilms.
