The molecular features that govern their bioactivity were explored through in silico docking experiments.
In addition to activating mechanisms of adaptive immunity, certain groups of allergens have molecular features that contribute to allergenicity.
Sykes reviews the clinical trial results and explains the experimental techniques used to study the molecular features that predict tolerance and low rates of organ rejection in patients.
The new instrument, called a mass cytometer, promised to more than double the number of molecular features that could be measured simultaneously in each cell.
Strikingly, upon further development, the PASE exhibits cellular and molecular features that mimic the development of the posterior primitive streak (PS), with a requirement for SNAI1 to fully deploy epithelial-to-mesenchymal transition and cell dissemination.
The analysis of the structure activity relationship of these compounds could help to elucidate the main molecular features that contribute to the activity of these compounds.
I will discuss some of the key molecular features that distinguish the hepatocyte polarity phenotype from that of monopolar, columnar epithelia.
Attempts to correlate the structure of each sulfobetaines with its effect on folding revealed some molecular features that appear important in helping renaturation.
Finally, during a third phase, axons and dendrites develop an elaborate architecture, acquiring special morphological and molecular features that commit them to their final identities.
In this chapter, we describe two murine models developed for progeria research, named LmnaG609G/G609G and Zmpste24−/−, assessing the physical and molecular features that characterize them.
Additionally, we note that experiments with designed single-span transmembrane helices offer fundamental insights into the molecular features that govern protein lipid interactions.
