Sentence examples for molecular features including from inspiring English sources

Epigenetic mechanisms are regulated by various molecules and molecular features, including DNA and histone modifications, in a locus-specific manner.

Figure 3 summarizes our current knowledge on the associations of clinical, pathologic and molecular features including CIMP in colorectal cancer.

An association of each variable with CIMP-high was also assessed in strata of important clinical or molecular features, including age (<65 year old vs. ≥65 year old), sex, tumor location (proximal vs. distal), MSI status, and BRAF status.

We found that E11.5-E14.5 corresponds to a FL hematopoietic expansion phase with distinct molecular features, including the expression of new transcription factors, many of which are novel KRAB (Kruppel-associated box -containing zinc finger proteins.

These results indicated the existence of complex relations between clinical and molecular features (including CIMP) in colorectal cancer, which are summarized in Figure 4. Molecular classification by MSI status is increasingly important in colorectal cancer [38] [40].

As a potential antibacterial agent used in therapy, KP34 molecular features including genome sequence and protein composition were examined.

Among these, the most prominent molecular features include enhanced expression of the transcription factors Snail 1 and 2 (SNand and SNAI2- aka Slug) as well as SIX1, TWIST, and ZEB 1 and 2. Many of these developmental transcription factors are hijacked from their normal roles in maintaining tissue homeostasis, and their functions center around the TGF-β super family [25].

Molecular features included pretreatment RNA transcript levels, mutation status, copy number variation, and promoter methylation status.

Molecular features include transcription factors, neuropeptides, calcium-binding proteins, and receptors these interneurons express, among many others.

Available scientific literature indicates that the clades referred to as IV and V, displaying peculiar molecular features, include a few homologs playing a major role in PM susceptibility in monocots and dicots, respectively [ 21, 22].

Cox proportional hazards model was used to assess prognostic and predictive role of PIK3CA mutation, adjusting for clinical features and status of routine standard molecular pathology features, including KRAS and BRAF mutations and microsatellite instability (mismatch repair deficiency).