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It has been shown that SAC has a worse prognosis and different histological and molecular features compared to conventional carcinoma (CC) but, to date, there is no study analysing its methylome profile.
Our global analysis of molecular correlates of EGFRvIII and other deletion mutations revealed that, for the most part, tumors with these mutations were also not distinguished by specific molecular features compared to their wild-type RTK-amplified counterparts.
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According to our results the L-OHP resistant cells displayed altered cellular and molecular features as compared to the parental cells.
Additionally, tumours were divided in groups based on molecular features and compared with respect to patient's age at diagnosis, sex, family history of colorectal cancer, tumour sub-localisation, Dukes' stage and differentiation.
Although these tripeptidic BACE1 inhibitors contained some natural amino acid residues, they are expected to be useful as lead compounds for developing the next generation BACE1 inhibitors, due to their low molecular size and unique structural features compared with previously reported inhibitors.
Nanotechnology is thus the set of methods and techniques for processing matter on atomic and molecular scales to create products with both special and improved chemico physico features compared to conventional products.
Therefore, these compounds show similar (supra molecular features compared with other biologically active phospholipids, namely lysolecithin and platelet activating factor (PAF) [5].
To investigate the relationship between Lin28B and the uridylation pathway, we first intensively compared molecular features of Lin28A and Lin28B.
In order to gain insight into molecular features for alkaline adaptation, we compared BSP165 MAN with previously reported GH5 β-mannanases.
In this study, we compared the molecular features among basal-like tumors with and without BRCA1 mutations.
Schwandner et al (2000b) investigated the prognostic value of the apoptotic index compared to molecular features of rectal carcinomas and they found that apoptosis did not possess a prognostic role, whereas p53 was an independent predictor for both recurrence and survival.
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CEO of Professional Science Editing for Scientists @ prosciediting.com