Sentence examples for molecular features characteristic from inspiring English sources

The innate immune system detects infection via germline-encoded receptors recognizing conserved molecular features characteristic of microbes (Janeway 1989).

Known molecular features characteristic for BRCA1-mutated breast tumors are 1) a high degree of genomic instability due to homologous recombination (HR) deficiency [ 18], 2) a distinct pattern of genomic aberrations [ 19- 22] 3) a high frequency of TP53 mutations and 4) a high incidence of complex, protein-truncating TP53 mutations [ 10, 23].

There are several known molecular features characteristic for BRCA1-mutated breast tumors: 1) increased numbers of genomic aberrations, 2) a distinct pattern of genomic aberrations, 3) a high frequency of TP53 mutations and 4) a high incidence of complex, protein-truncating TP53 mutations.

Consequently, the aim of this study was the geographic analysis of RKIP expression in all histological areas of CRC and to determine the correlation of RKIP expression pattern with clinicopathological characteristics, molecular features and survival outcome.

Specifically, we addressed four topics for claudin-low tumors including (1) molecular features, (2) clinical and histological characteristics, (3) relation to established breast cancer cell lines and genetically engineered mouse models and (4) differentiation status based on analyses of purified normal mammary epithelial cell subpopulations.

A feature of anthracyclines and other topoisomerase II inhibitors, is that, at least in part, these different characteristics derive from distinct molecular features and can be functionally separated.

Furthermore, over 90 hereditary conditions in horses have corresponding human disorders [ 3, 6], and many muscle disorders in humans and horses share common clinical and histopathological characteristics, as well as molecular features [ 7- 9].

Table 1 summarizes different characteristics and prognosis based on molecular features (statistical comparisons exclude the ER-PR+ subgroup).

Here we review the morphological and molecular features that underpin the disparate biological and clinical characteristics of this fascinating tumour type.

These characteristics of egfp-CCAT1-L resemble known molecular features of the endogenous CCAT1-L.

Because breast cancer is heterogeneous with respect to clinical, histopathological and molecular features, several subclassifications have been investigated to stratify tumors with similar characteristics.