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Understanding these complex cellular responses requires the detailed analysis of global molecular expression profiling.
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Molecular expression profiles can uncover clues to functionally important molecules in the development of human disease and generate information to sub classify human tumors and tailor a treatment to the individual patient.
Molecular expression profiles can uncover clues to functionally important molecules in the development of human disease and generate information to subclassify human tumors and tailor a treatment to the individual patient.
To evaluate the effects of STAT3-CKO on the appearance and various molecular expression profiles of astrocytes in vitro, we used primary astrocyte cultures that are over 95% GFAP-expressing cells [21], [22].
Distinct molecular expression profiles distinguishing between good and bad prognosis in RCC were identified [ 15- 26].
For example, basal like cancers have distinct molecular expression profiles and histological differences when compared with the luminal type [ 42].
Systems biology study provides a new technology platform that can reveal molecular expression profiles associated with different morphological developments.
Molecular expression profiles were obtained from the Sex Bias Database (SEBIDA version 2.0: http://141.61.102.16:8080/sebida/index.php; Gnad and Parsch 2006).
The DNA damage potential and mechanisms for different ENMs seemed to vary and were concentration- and species-dependent, as indicated by the distinct altered molecular expression profiles.
Statistical analysis of IHC and molecular expression profiles and correlation with histological parameters and follow-up data were performed with the SPSS advanced statistical package 13.0 (SPSS Inc., Chicago, Illinois).
As for an example, it is very well understood that malignancies can be identified based on their molecular expression profiles [ 1, 2].
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