JSP participated in the molecular experiments, gene expression analyses and the writing of the article.
The model has been subjected to multiple molecular profiling and gene expression analyses.
Complete transcriptome sequencing has generated species specific molecular markers, in silico expression analyses, gene discovery, and phylogenetic relationships [ 43, 44].
The homologous sequences TaIPS1.1 (accession number EU753150), TaIPS1.2 (EU753151), and TaIPS1.3 (EU753152) have been isolated and deposited in GenBank, but molecular studies, such as expression analyses, have not been reported.
It has become very common for molecular biology laboratories to use global gene expression analyses to understand the molecular signature of a cell.
Roth, R. B. et al. Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.
The intrinsic molecular subtypes based on gene expression analyses (Perou [ 2], Sorlie [ 3]) are for practical purposes approximated using clinicopathological criteria.
In our study, the functional link between HMGA1 and IGFBP-3 was initially evaluated by molecular biological techniques and gene expression analyses in both T/C-28a4 and C-28/I2 chondrocytic cultured cells, which are two in vitro cell models that are commonly used for studies on articular cartilage pathophysiology [ 30].
Thus, a possible way to investigate the molecular pathways in inflammatory myopathies is to analyse the molecular expression patterns in the target organ, the skeletal muscle (for example, from patients in different phases of disease), and to correlate these molecular findings with clinical outcome measures (for example, muscle strength tests).
Future promise is via application of new techniques such as metabolic engineering, accomplishing quantification, and control of metabolic fluxes including inverse metabolic engineering, transcript expression analyses, directed evolution, molecular breeding, and combinatorial biosynthesis.
