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This discrepancy could at least partially be explained by the slow pace of molecular evolution observed for woody plants, which is related to the lengthy generation time of these species [ 37].
Our study reveals a case of subterranean convergent evolution in rodents that is correlated with change in the pace and mode of molecular evolution observed at the genome scale.
Thus, although it is not surprising that functional constraint as reflected in ω would vary across a protein, the signatures of molecular evolution observed for the songbird TAS2Rs were reminiscent of what had been seen before in humans and other mammals.
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In the other case, molecular evolution was observed, and the failure to attain the optimum was interpreted as a failure of the model used to calculate the optimum (that the assumed trade-off did not match the T7 trade-off).
The pattern of molecular evolution we observe for Sex-lethal and its paralogue sister-or-Sex-lethal is not characteristic of a duplication followed by neo-functionalization.
Parallel molecular evolution is frequently observed in experimental population studies, particularly in microbial systems [ 53– 53].
It is also possible that the positive association between rates of molecular evolution and clade size observed in some taxa is not due to a direct effect of speciation on molecular evolution, or vice versa, but the result of another variable driving both processes independently of each other, leading to an indirect correlation between the two.
It is therefore possible to observe molecular evolution at unprecedented resolution, such that 1) the age of gene gain events can be accurately mapped to a species phylogeny and 2) many gene loss events can be observed as pseudogenes.
Substantial differences in the rates of molecular evolution in different plant lineages observed by Smith and Donoghue could lead to differences in how long it takes for a duplicated gene to return to single copy through either through random or unknown nonrandom (selective) processes.
Students literally observe phenotypic and molecular evolution in their classroom!
It has been observed that the overall molecular evolution of the catalytic pockets dictates the choice of substrates/products of the proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com