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The frequency of convergent adaptive molecular evolution, however, remains an open question.
It is largely displaced in molecular evolution, however, by a formalism based on statistical language, including reversed Markov Chain models, and the "approximate methods" discussed by Yang and Nielsen [ 6].
It is difficult to predict the influence of variation in extinction rates on rates of molecular evolution, however some theoretical models do predict a link between speciation and rate of molecular change, and it is possible that this is the underlying cause of the relationship.
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However, molecular evolution leading to adaptation is a complex issue and all fast-evolving and putative positive selected genes identified in this study may or may not be related to hibernation per se in bear.
Sleep has been conserved throughout evolution; however, the molecular and neuronal mechanisms of sleep are largely unknown.
Future comparative analyses of ψND5-1 molevolutionolution between these two species, however, might provide important insights into the role of outcrossing in eliminating deleterious mutations from natural populations.
However, the divergent molecular evolution of ribosomal genes and protein-encoding genes specifically the bias against transversion events in coding genes of conserved function suggests that deployment of multiple parameter sets could outperform the use of a single parameter set applied to all molecules.
However, models of molecular evolution that aim at reconstructing the evolutionary history of macromolecules become computationally intractable if such correlations between sites are explicitly taken into account.
However, evidence for potentially adaptive molecular evolution has been uncovered as well.
However, accumulating evidence supports a molecular evolution of breast cancer during its life cycle, with metastatic lesions acquiring new molecular aberrations.
However, several questions remained regarding the molecular evolution of glpO in mosquito-associated Spiroplasma species.
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