Sentence examples for molecular evolution approaches from inspiring English sources

To conclude, that pharma and biotech companies should actively seize upon the potential of computational molecular evolution approaches in their translational research.

The presence of G116, G117, and E197 variants discovered from both rational and molecular evolution approaches shows the importance of the approach to identifying residues in nerve agent model compound resistance.

Molecular evolution approaches and the software package Phylogenetic Analyses by Maximum Likelihood (PAML) were utilized to investigate the signature of selection that has acted on the mammalian CC chemokine receptor (CCR) gene family.

The second plasmid for CYP106A2 expression was constructed with all features necessary for a molecular evolution approach.

Moreover, because the genomic segments used in this study were sampled along the genome, it was expected that the rate of molecular evolution approached the neutral evolutionary rate.

Previously, we described a robust directed molecular evolution approach to identifying hBChE residues that conferred resistance to enzymatic inhibition by nerve agent model compounds.

Because H2AB has not been previously characterized, we used a molecular evolution approach to investigate its relationship to H2A variants that have been characterized more thoroughly.

Complementary to the molecular evolution approach is the idea of examining variation in gene expression between tissues, individuals, populations, and even species.

To identify hBChE variants that showed resistance to inhibition of functional activity by nerve agent model compounds, we implemented a directed molecular evolution approach in a mammalian cell -based functional screen.

One molecular evolution approach that supports this adaptive function for MHC genes is the higher rate of nonsynonymous (amino acid changing) to synonymous substitutions at functionally important amino acid positions (for a summary of tests at MHC, see Garrigan and Hedrick 2003).

Using a molecular evolution approach, the positive selection (dN/dS > 1) of genes along branches leading to each seagrass species was investigated to identify candidate genes in which adaptations allowed for the transition from a terrestrial to an aquatic - and ultimately marine - lifestyle.