Sentence examples for molecular events consistent from inspiring English sources

Thus, compound 5b restores the p53 function, which triggers molecular events consistent with cell cycle arrest at G1/S phase.

Treatment with PTC‐209 reduced protein level of BMI‐1 and its downstream target mono‐ubiquitinated histone H2A and triggered several molecular events consistent with the induction of apoptosis, this is, loss of mitochondrial membrane potential, caspase‐3 cleavage, BAX activation, and phosphatidylserine externalization.

We demonstrate that exposure of proliferating colorectal cancer cells to oxaliplatin induces a G2/M arrest and a molecular cascade of events consistent with an intrinsic mechanism of apoptosis.

Although these metabolic signatures are often different for different classes of agents, they are on the whole consistent with the molecular events triggered after challenge with a particular targeted therapeutic, for example, inhibition of ChoK or activation of phospholipases.

Further investigation revealed that the molecular events in simvastatin-induced cell death are consistent with classical apoptosis marked by proteolytic cleavage and activation of caspases.

While the molecular events in the livers of these patients are unknown, this clinical setting is consistent with our model (Fig 8) in which statin-induced miR-33 represses both ABCB11 and ATP8B1, thus decreasing bile secretion and eventually leading to intrahepatic cholestasis.

The big picture is real and cannot simply be reduced to molecular events.

In his efforts to understand why the heart muscle weakened, Dr. Marks focused on the molecular events in the heart.

Molecular events impact systemic dissemination.

Several molecular events are associated with this transition.

Likewise, the molecular events driving leukemogenesis remain elusive.