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Here, a self-inhibitory peptide is stripped from the switch region of TnI interaction interface with TnC, which is considered as a lead molecular entity and then used to generate potential peptide disruptors of TnC TnI interaction based on a rational molecular design protocol.
Molecular data sets for clustering consist of input vectors where each vector represents a molecular entity and consists of a set of molecular descriptors itself.
We have used Pipeline Pilot in this project to render the image for a molecular entity and also to run the OSRA protocol to capture the images and store them into the database.
An important goal in future research will be to determine the ultimate molecular entity and the operative molecular mechanism through which RecA allows swarming motility in E. coli to proceed.
We further adapt and evaluate named entity and event extraction methods for the new task, demonstrating that both can be achieved with performance broadly comparable with that for established molecular entity and event extraction tasks.
Repurposing drug screens are done in the hope that the time to clinical efficacy trials will be considerably shorter than for a new molecular entity and, at least in theory, that retail prices will therefore be lower (Dueñas-González et al., 2008).
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The normal-mode frequencies will tend to be associated with intramolecular motions of specific molecular entities and will be found to have values lying in a relatively narrow frequency range for all molecules containing that entity.
The use of diazinedicarboxylate ligands in the construction of preconceived molecular entities and crystal structures deserves a good understanding of their coordination capacity in order to employ them for their rational design of functional materials.
A set of recommendations is provided to improve standards for integrating age and sex into the study design, analysis, and reporting of pre-clinical and clinical assessment of new molecular entities and biologics in adults.
This predictable behaviour has led to the development of spectral correlation charts that can be compared with observed infrared spectra to aid in ascertaining the presence or absence of particular molecular entities and in determining the structure of newly synthesized or unknown species.
Examples are 'carbon molecular entities' and 'lanthanoid molecular entities'.
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molecular features and
molecular organizations and
molecular spectroscopy and
molecular level and
molecular geneticist and
molecular analysis and
molecular cloning and
molecular pathology and
molecular profiling and
molecular gastronomy and
molecular replacement and
molecular recognition and
molecular biology and
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