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Three vaccines (named C, D and F) against the p40 were developed by inserting peptides derived from p40 into the carrier, hepatitis B core antigen, using molecular engineering methods.
Soluble recombinant expression of pharmaceutical proteins is of utmost importance not only for direct applications but to be able to employ advanced molecular engineering methods to alter their physicochemical properties.
By combining various molecular engineering methods, including alanine scanning, site-directed mutagenesis, computational structure-based design/algorithm and experimental selections [60], [61], [63], [64], a large set of Fc variants has been generated to provide a broad spectrum of FcγR-binding profiles.
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Peptide aptamers (32 amino acids in length) were screened from a random peptide library by in vitro peptide selection using the evolutionary molecular engineering method "cDNA display".
In this issue of Chem, Liu and coworkers report a rational molecular engineering method of preparing two-electron-storage viologen compounds as negative electroactive materials for aqueous redox flow batteries.
Even though the term has little meaning, "GMO" has come to denote modern molecular genetic engineering methods used to achieve specific, targeted traits, from insect and disease resistant crops to apples that don't turn brown.
His laboratory is based in the James H. Clark Center at Stanford and employs a range of techniques including neural stem cell and tissue engineering methods, electrophysiology, molecular biology, neural activity imaging, animal behavior, and computational neural network modeling.
Recent advances in the understanding of phytoalexin function, biosynthesis and regulation, in combination with novel methods of molecular engineering and advances in instrumental analysis, returned attention to phytoalexins as a potent target for improving crop protection.
A novel and efficient method for molecular engineering of the pore size and porosity of microporous sol gel silica membranes is demonstrated in this communication.
Based on Molecular Engineering and Crystal Engineering concepts, a new method for designing nonlinear optical (NLO) crystal materials, the Organic Inclusion Complex (OIC) method has been demonstrated.
For these reasons, TAM receptor targeting represents a uniquely interesting context to investigate how we might develop fundamentally new approaches to cancer therapy and to use engineering methods to accelerate reverse-engineering molecular systems.
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