Three vaccines (named C, D and F) against the p40 were developed by inserting peptides derived from p40 into the carrier, hepatitis B core antigen, using molecular engineering methods.
Soluble recombinant expression of pharmaceutical proteins is of utmost importance not only for direct applications but to be able to employ advanced molecular engineering methods to alter their physicochemical properties.
By combining various molecular engineering methods, including alanine scanning, site-directed mutagenesis, computational structure-based design/algorithm and experimental selections [60], [61], [63], [64], a large set of Fc variants has been generated to provide a broad spectrum of FcγR-binding profiles.
A novel and efficient method for molecular engineering of the pore size and porosity of microporous sol gel silica membranes is demonstrated in this communication.
Recent advances in the understanding of phytoalexin function, biosynthesis and regulation, in combination with novel methods of molecular engineering and advances in instrumental analysis, returned attention to phytoalexins as a potent target for improving crop protection.
Based on Molecular Engineering and Crystal Engineering concepts, a new method for designing nonlinear optical (NLO) crystal materials, the Organic Inclusion Complex (OIC) method has been demonstrated.
Molecular engineering refers to a collection of complex, computer-based methods used to study molecular structures and properties.
Our optimized conditions have improved the yield of cDNA display molecules by more than 10 times over currently used methods, making cDNA display more practically available in evolutionary molecular engineering.
We are also strengthening links with chemical engineering, and with regional, national and international chemical industries through the molecular engineering initiative, which is developing strongly here.
