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Although the correlations between the cytogenetic and molecular effects and clinical efficacy have been well established, previous studies have provided little information about the in vivo metabolism of CML patients during imatinib treatment, except in terms of bone and mineral metabolism [24], hyperlipidemia [25], creatine kinase, phosphate, and phosphocholine [26] [27].
Addition of DHA further increases both of these molecular effects and increases uptake of CCM by SK-BR-3 cells.
Particularly, the standard syntax of mutation description is critical for its sustainable utilization in both molecular effects and biological functions.
Thus, the model could have important applications for assessing the molecular effects and functional benefits of forthcoming therapies in individuals with different types of muscular dystrophy.
In order to investigate the molecular effects and the possible drivers that induced autophagy following DCA treatment, the mTOR pathway was examined in DCA-treated colorectal cancer cells.
In this study we aim to better characterize molecular effects and efficacy of sorafenib against thyroid carcinoma cells with various histological origins and different BRAF mutational status.
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Both the molecular effect and electrical effects by the conducting polymers appear to play an important role in hydrogen sorption.
Here statistical power depends on the allele frequency and magnitude of the biochemical or molecular effect, and small numbers of subjects are usually adequate.
We divided each treatment group into 2 subgroups; one group to assess the immediate molecular effects (TP1) and one group for the tumor growth delay assay (TP2).
In particular, future studies need to consider the mechanism of action and molecular effects of IACFM, and explore the impact of dosage variables.
Because the liver is a known target of arsenic, we examined the pathophysiologic and molecular effects of inorganic and organic arsenical exposure on Tg.AC mouse liver in this study.
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