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These findings suggest that alcohol degrades the "molecular brake pads" inside the reward circuitry of the brain, specifically histone deacetylases 4 and 5, much like previous research has suggested nicotine has the same molecular effect on the brain.
Mood disorders often display disturbances in circadian rhythms that are manifested as abnormalities in sleep stage and various physiological domains, clinical efficacy of sleep deprivation [2], [3], and a molecular effect on the circadian clock by lithium [4], which is commonly prescribed for bipolar disorder.
Nevertheless, the possible molecular effect on miR expression was studied in the case of the novel pre-miR-16-1 variation.
However when the variant is co-inherited with a pathogenic mutation it worsen the disease phenotype which suggest a possible molecular effect on protein features as suggested by the Grantham Matrix Score (Table 1).
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What is the molecular effect of TCZ on target cells?
However, the molecular effect of hypoxic stress on VHL functions remains elusive.
The molecular effect of the founder mutation on ADAMTSL2 is formation of disulfide-bonded dimers.
Vecsey, C. G., Pirez, N. & Griffith, L. C. The Drosophila neuropeptides PDF and sNPF have opposing electrophysiological and molecular effects on central neurons.
Moreover, the mechanisms of penetration enhancement and the micro molecular effects on the skin stratum corneum were investigated using attenuated Fourier transform infra-red spectroscopy.
Molecular effects on regulation of transporter proteins may aid in understanding epileptogenesis and inform investigators about future design and development of drugs to treat epilepsy.
Here, we developed a 9-plex bead-based array as a tool to evaluate molecular effects on transcription levels of immune-related genes in the black tiger shrimp (Penaeus monodon).
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