Sentence examples for molecular driver of from inspiring English sources

These studies identified B cell lymphoma-9 (BCL9) as a potential molecular driver of early invasion.

In this manuscript, we provide evidence that BCL9 serves as a molecular driver of epithelial mesenchymal transition (EMT) and DCIS invasion by the enhancement of canonical Wnt signaling.

These results strongly point to the upregulation of TRAIL-R2 as the molecular driver of the 5-FU-induced sensitization effect.

BCL9 is a molecular driver of DCIS invasive progression and may predispose to the development of basal like invasive breast cancers.

Cyclin D1 oncogene activation is a prevalent molecular driver of human cancer, playing key roles in breast, squamous cell, esophageal carcinoma, mantle cell lymphoma, multiple myeloma, and many other devastating human malignancies.

Furthermore, with the emergence of ALK as a molecular driver of a number of other cancer types, including non-small-cell lung cancer, diffuse large B-cell lymphoma, breast cancer, retinoblastoma, colon carcinoma and esophageal squamous cell carcinoma, we believe that detection of MSH2 phosphorylation at Y238 may be of great clinical and diagnostic significance.

Development of the new drugs has been spurred by the falling cost of decoding DNA and the prospects of premium prices for drugs that specifically attack the molecular drivers of cancer.

As well as providing the molecular drivers of cancer, changes to the DNA also cause the diversity within a cancer tumor that makes it so hard to eradicate completely.

When molecular drivers of healthy adipogenesis are perturbed, this can cause hepatic steatosis.

To this end, enhanced precision tools must be developed to describe the molecular drivers of malignant proliferation.

Over the past several years, renewed effort in cancer research has yielded a myriad of molecular drivers of and contributors to tumour progression.