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The advent of unbiased molecular discovery technologies offers new opportunities to identify novel pathogens without the constraints imposed by assays selective for known or expected agents.
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The ActinoDrug staff is going to grow soon, and motivated young molecular biologists are highly welcome to join us for the further development of drug discovery technologies.
Rader, D. J. & Daugherty, A. Translating molecular discoveries into new therapies for atherosclerosis.
Rather, it was probably a series of published observations, experiments, and discoveries enabled by increased molecular and genomic technologies that led to the discovery of this association.
These advances in gene trapping, in combination with other molecular genetic technologies such as microarrays and site-specific recombination, provide the individual investigator with powerful tools for gene discovery and vascular development.
His research program is motivated by the idea that innovative molecular technologies can spawn biological discovery.
She takes new discoveries in molecular and biological technology, breaks them down into their simplest forms, figures out ways to replicate them at lower costs and then transfers the information to public health workers in the developing world.
Application of molecular diagnostic technology in the past 10 years has resulted in the discovery of several new species of pathogenic rickettsiae, including Rickettsia felis.
Though there has been marked progress in the field of molecular signature discovery in recent years, there remains a clear need for further improvements in the discovery process in order for omics-based technologies to begin to achieve their full clinical potential.
Using high-throughput molecular technologies, large collaborative projects such as the European Commission-funded MetaHIT and the US NIH-funded HumareMicrobiome Project aidingding the discovery of increasingly important insights into the role of the microbiome in human health.
More recently, technological changes in DNA sequencing, including the recently introduced 'NextGen' instruments and associated molecular technologies, have enabled both higher-throughput and more sensitive assays that provide important new opportunities for basic discovery and clinical application (Mardis, 2009).
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