Sentence examples for molecular determinants modulating from inspiring English sources

It might also be of interest to understand the molecular determinants modulating SAMHD1 expression.

To gain insight into the molecular determinants that modulate the inhibitory activity of these compounds, a molecular modelling study was performed to explore their binding to the enzyme.

Hence, the ES cells maintenance and the differentiation need to be tightly regulated opting between the permissive and instructive mode of differentiation and the threshold of specific molecular determinants might modulate the balance between the two.

The molecular determinants that modulate the course of trauma-induced and genetically-induced spinal cord degeneration are still largely elusive.

This interaction that relies on specific Cav3.2 molecular determinants, not only modulates T-type channel activity, but was also found essential to support low-threshold exocytosis upon Cav3.2 channel expression in MPC 9/3L-AH chromaffin cells.

Unfortunately, we were not able to determine the molecular determinants of these phenotypes in this study.

Improved understanding of those molecular determinants may contribute to the design of subtype selective channel modulators.

These structures elucidate the molecular determinants underlying polyproline ligand selection by the FE65 WW domain and provide a framework for the design of small molecules that would interfere with FE65 WW ligand interaction and modulate neuronal development and APP signaling.

Neurotrophic factors have been identified as molecular determinants of PNI.

However, molecular determinants of this ion channel blocker are unknown.

Intrinsic molecular determinants of neurodevelopmental outcomes assume new, albeit related roles during adult neural regeneration.