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Here, we provide a comprehensive overview of the current literature on the ligand structures detected by RIG-I, and conclude with the molecular definition of the RIG-I ligand: short double-stranded blunt-end 5′-triphosphate RNA.
An interesting empirical investigation of scientists' use of gene concepts found that, in their work, molecular and evolutionary biologists favored Gene-P and developmental biologists favored Gene-D, but when asked explicitly, all biologists preferred a molecular definition of the gene (Stotz, Griffiths, and Knight 2004).
The Human Genome Project was the first step in a globalized effort to incorporate accumulated knowledge of biology into a functional, molecular definition of the human body and the bodies of other organisms.
Our objective was to develop a consistent molecular definition of psoriasis.
However, a precise molecular definition of MSC and the sequel of long-term in vitro culture are yet unknown.
These comparisons will sharpen the molecular description of each cell type and in particular the molecular definition of pluripotency [35].
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Deeper molecular definitions of tumor-infiltrating-lymphocytes could thus offer therapeutic opportunities.
In this study a series of epistatic cases that are quantitative in nature but based upon such biological or molecular definitions of epistasis are considered.
In spite of all the recent progress in this area, the cytological and molecular definitions of (hetero chromatin have not yet been conclusively and comprehensively linked together.
While heterochromatin was described cytologically in 1928 as intensely stained parts of chromosomes that remain condensed over the cell cycle (Heitz, 1928), molecular definitions of heterochromatin remain elusive.
In 2051 we will not be talking about syndromes but rather about molecular definitions of and genetic predisposition to disease, as well as about activation of specific pathways that lead to organ dysfunction.
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