Sentence examples for molecular defects affecting from inspiring English sources

Unsurprisingly, molecular defects affecting polarity organization and functions have a strong impact on tissue homeostasis, embryonic development and adult life, and may directly or indirectly lead to diseases.

Heterogeneous molecular defects affecting the 11p15.5 imprinted gene cluster are associated with the congenital growth disorders, Beckwith Wiedemann syndrome (BWS) and Silver Russell syndrome (SRS) (8, 9).

Discovering how mutations in these genes cause cellular and molecular defects affecting axons will enhance our understanding of the etiology of HSPs and contribute to the development of effective treatments.

Individuals with BWS have heterogeneous molecular defects affecting one or both domains of the cluster, including paternal uniparental disomy (UPD) or duplication, CDKN1C mutations and IC epimutations and microdeletions.

These subtypes have distinct underlying molecular defects that affect both their aggressiveness and the signaling pathways that are vulnerable to targeted therapies [ 3, 4].

Moreover, the SMA-causing genes are mostly ubiquitously expressed and their molecular defects can affect other tissues, causing, for example, diverse laminopathies (LMNA), skeletal dysplasias (TRPV4), and malformations of cortical development (DYNC1H1).

Toyota has recalled more than 8m vehicles worldwide for safety defects affecting some of its bestselling models.

Or maybe the semen analysis can't pick up subtle sperm defects affecting fertilization.

The genetic determinants of individual clinical cases are increasingly being described, but how these genetic defects affect complex I on the molecular and cellular level, and have different clinical consequences in different individuals, is little understood.

Crystalline defects affect the quality of the explosives.

These defects affected suckling but not breathing.