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Molecular databases, on the other hand, make it possibleto compile datasets in a more interactive manner.
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The Molecular Databases page which is based on Entrez, the integrated search and retrieval system developed by the NCBI has more than 25 additional database classifications such as nucleotide, protein, and expression.
The basis of this system consists of chemical compounds from PubChem which were mapped on thirteen molecular databases.
Microarrays and other new high-throughput technologies of the past decade have made it possible to generate large molecular profile databases on clinical cancers and cultured cancer cells.
The sequences were submitted to NCBI molecular database.
Gene set collections associated with stress functions were obtained using a gene set browser (Molecular Signatures Database v3.0) on the Broad institute website (http://www.broad.mit.edu/gsea/), as previously described [ 14] using the keywords such as 'apoptosis', 'hypoxi*' and others.
There are hundreds of publicly available databases on drug discovery Protein Data Bank (PDB) [12], DrugBank [13], Kyoto Encyclopedia of Genes and Genomes (KEGG) [14], ZINC [15], Chemical database of European Molecular Biology Laboratory [16], and Therapeutic Target Database [17].
Pathways were downloaded from the Gene Set Enrichment Analysis (GSEA) molecular signature database [ 12] on Oct. 9, 2009.
In an experiment to compare author-contributed findings with expert curation in the MINT (Molecular INTeraction) database, author recall on curating protein protein interaction was reported at 57% compared with curator recall of 87%, measured against a curated gold standard (11).
Gene set enrichment analyses (GSEA) [ 7, 8] are commonly used to determine the biological characterization, statistical significance, and concordant differences between an experimental gene set and a selected gene list from annotated gene sets knowledge base stored on Molecular Signatures Database (MSigDB).
A Venus atmosphere model, molecular line databases, a cloud model, and a radiative transfer calculation are necessary to calculate the brightness distribution on the Venus disk.
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