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Signals persisting in treatments with enzyme alone (lanes 3) correspond to RNA and protein encapsulated (protected) by the GC membrane, and correspond to the specific molecular content of isolated GCs.
The multimodal approach presented above enables the measurement of two sets of information, with the Raman channel providing spectral information related to the molecular content of the sample, and the phase measurement being a quantitative indicator of the sample dynamic morphology.
The cellular and molecular content of platelet concentrates also depend on the method or kit used for their preparation.
The molecular content of the mouse hippocampus extracts was determined via manual data analysis using the mass spectrometer software, DataAnalysis (Bruker Daltonics).
We are currently analysing the molecular content of these vesicles, the role of CIP4 in their generation and their impact on T cell biology.
After GCE treatment the light scatter patterns became less diffuse and more concentrated, indicating a change in size, granularity and molecular content of the cells.
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This means the ability to screen the varied molecular contents of individual cells.
This is usually obtained by the analysis of the molecular contents of live cells [ 41].
As a result, analytical techniques that provide detailed information about the exact molecular contents of today's high-solids formulations have become necessary tools for characterization.
In order to detect the molecular contents of each vesicle at the single molecule level, Luisi et al. used cryo-TEM, which is a very reliable method for imaging lipid vesicles.
The state of knowledge on biogenesis, molecular content and horizontal communication of diverse types of cancer EVs has expanded considerably in recent years.
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