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Modern genetics, he pointed out, uses molecular concepts but also original Mendelian ones; for example, molecular concepts are used to explain, not to replace, the Mendelian notion of mutation.
In general, there are few cellular and molecular concepts integrated into these organismal topics.
The rationale behind these arguments, their underlying molecular concepts and strategies towards therapeutic application will be discussed.
The chemical basis of these molecular concepts is put into perspective with the uptake and intracellular activation mechanisms, the in vitro and in vivo proofs of concepts and the clinical results.
The surgeon notes that basing the formation of an image on a molecular process would be compatible with current medical practice, which utilizes molecular concepts to base medical decisions.
This article discusses the various classes of immunomodulatory biomaterials and advocates a cross-disciplinary approach that brings together molecular concepts from various fields to rationally design vaccine adjuvants with immunomodulatory properties.
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Rosenberg concluded that since the relation between molecular genes and Mendelian phenotypes is exceedingly complex, the connection between any molecular concept and the Mendelian gene concept must also be exceedingly complex, thereby blocking any systematic, reductive explanation of classical genetics in terms of molecular-level theory.
We explored numerous associations among diagnoses in our electronic medical record using the Molecular Concept Maps (MCM) web application.
However, due to the nomination of higher number of aaRSs from iTRAQ experiment, molecular concept network with combined data set showed a set of interconnected aaRS concepts with significant scores (Figure 4).
We employed an analytic approach original developed for detecting associations between sets of gene expression data, called Molecular Concept Map (MCM), to find significant associations among the 1.5 million clinical problem summary list entries in 327,000 patients from our institution's EHR.
Molecular Concept Maps (MCM) software [31] and the ClueGO [32] Cytoscape plugin offer a richer visualization solution than DAVID, displaying enriched gene-sets as a network, where each gene-set is represented as a node and edges connect similar gene-sets.
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