Although critical for development, the molecular composition and related physical properties of the embryonic sheath remain poorly characterized.
Structural and molecular composition of the ECM changes during development, becoming denser and more rigid in the mature brain (Frischknecht and Gundelfinger, 2012; de Vivo et al., 2013).
The dynamic molecular composition of synapses is crucial for the development and fine-tuning of nervous systems to external cues.
The molecular composition of choroidal TJs is regulated during development, as exemplified by the coordinated up– or down regulation of specific pore forming and tightening claudins that make up the core of the junctional complex [ 15].
Since AISs differ from nodes of Ranvier in terms of molecular composition (hence of molecular clustering mechanisms) and development (AISs are preorganized when myelination takes place), would this first myelin-anchoring region resemble a hemi-node of Ranvier: would the AIS be, like nodes of Ranvier, flanked by a paranode-like and a juxtaparanode-like compartment?
A different molecular composition of presynaptic and postsynaptic NMDA receptors during development raises the possibility that different NMDA receptor subunits are required for t-LTD and t-LTP (Corlew et al. 2008).
Because bee venom is a human toxin, a comprehensive characterization of its molecular composition, side effects, and toxicology is of paramount importance for the development safe pharmaceutical formulations to satisfy human demand.
Despite intensive research, the precise coordination of this morphological transition, the changes in molecular composition, and the relation of spines of various morphologies to function remain a central enigma in the development of functional neuronal circuits.
We also discuss necessary development in methodology in order to have the highest impact on the study of the molecular composition of CSF proteins.
Amylin receptors: molecular composition and pharmacology.
