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The phenomenon of molecular collaboration of EGFR with other partners on cell membrane represents an important feature of cancer progression and may in part explain why targeted therapy designed to circumvent EGFR signaling has yielded only modest clinical success in cancer patients [ 93].
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To identify these areas of molecular synergism, close collaboration between basic researchers and clinical staff is critical.
The Hsp90 molecular chaperone, in collaboration with a plethora of co-chaperones, is involved in the assembly and stabilization of key regulatory proteins in the eukaryotic cell (Pearl and Prodromou, 2006).
In collecting FBB samples, we always keep in mind future biochemical and molecular analyses and collaborations.
The work represents "a really nice collaboration between molecular biologists and plant breeders," says Jan Leach, a plant pathologist at Colorado State University in Fort Collins.
The application of these advances to tissue engineering is likely to be an emerging focus of laboratories internationally, with well-integrated collaboration between molecular biologists and tissue engineers.
The success of molecular biology results from collaboration with computational mathematicians, whose algorithms can extract solutions from intractably large problems.
Reynaud E.G. carried out the molecular biology experiments, in collaboration with Ly T.B.N, the localization studies, the immunofluorescence and the cell biology studies.
For example, several respondents noted that the quantity and complexity of data analysis requires more effective collaboration between molecular biologists and computational biologists.
Finally, the model recapitulates a particularly poor prognostic form of AML with a major unmet need for novel therapeutic approaches and thus provides a powerful model for future studies of the cellular and molecular mechanistic bases for collaboration of these mutations in AML.
The future for microstructuring of surfaces for cell culture is expanding, and generating considerable cross-disciplinary collaborations between molecular biology labs, microfabrication centers, and materials science groups.
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