Sentence examples for molecular clockwork have from inspiring English sources

In the course of evolution, timekeeping mechanisms, such as the molecular clockwork, have evolved in all cells of the body.

Although some diversity in the molecular clockwork has been presented between the central and the peripheral clocks [ 13] and among insects [ 14], the functional roles of PER and CYC are considered to be identical - PER acts as a negative regulator and CYC acts as a positive regulator [ 9].

However, the functional significance and the regulating factors of the pituitary clockwork have not been documented to date.

Timed nuclear accumulation of members of the negative limb within the circadian clockwork has long been known to be critical for a functional circadian clock.

The l- and s-vLNs are the only PDF neurons that express the molecular clockwork, suggesting that the abdominal PDF cells do not have a direct role in the maintenance of rhythms.

Several pacemaker neurons and clock genes have now been identified and their roles in the cellular and molecular clockwork established.

Previous reports have suggested that CK1ε plays a role in temperature compensation of the molecular clockwork [ 22, 23].

Physiological outputs (hormonal, metabolic and cellular) that are entrained to the 24 hour cycle of the earth's rotation have been described in organisms from cyanobacteria through humans, and are based on molecular clockwork, [reviewed in 3], [34], [35].

In addition, transcriptome analysis and RNA-interference studies in cockroaches make functional studies of the molecular clockwork feasible despite of the large, not yet-sequenced genome of this cockroach species.

Figure 3: Time-of-day-dependent modulation of the molecular clockwork by PDF.

Preitner, N. et al. Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators.