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Recent estimates made using molecular clock methods (such as described above for Orthoptera) give estimates of 167 199 million year ago for the origin of flowering plants, in the Jurassic (Bell et al. 2010).
We performed dating analyses using two different relaxed molecular clock methods, which have recently been demonstrated to be the least sensitive to taxon sampling [36], and which have complementary advantages and limitations.
Molecular clock methods have estimated the origin of cyanobacteria at 2.56 Ga 2.04 3.08 Gaa) [ 30].
This is the first study to estimate divergence times within the oomycetes using molecular clock methods.
Dating these ancient divergences using molecular clock methods is even more difficult [ 1, 2, 19, 20].
Molecular clock methods therefore provide the only avenue for elucidating the evolutionary history of some lineages.
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Although this is the standard method, it is imprecise, Dr. O'Brien said, adding that this molecular clock method could be off by hundreds of years.
To verify their results, the researchers turned to the molecular clock method, which assumes a constant rate of genetic mutation to date a species.
Secondly, we used a relaxed (uncorrelated lognormal) molecular clock method [68] as implemented in BEAST version 1.4.6 [69].
A relaxed molecular clock method allowing autocorrelated rates of evolution along branches [64] was also implemented here.
Molecular divergence dates were calculated using the 20.1 kb molecular supermatrix of Beck [10] and the Bayesian relaxed molecular clock method implemented in BEAST 1.4 [26].
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