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But it is important to stress that the molecular clock is not exactly 24-hour, but a bit longer.
Although the molecular clock is present in innate immune cells, its role in monocyte homeostasis remains unknown.
During the 1970s and '80s it gradually became clear that the molecular clock is not exact; nevertheless, into the early 21st century it continued to provide the most reliable evidence for reconstructing evolutionary history.
These results indicate that PDF upregulates CLK/CYC-mediated transcription and PER levels in the LNvs and DN1s at night but not during the day, and this nighttime-specific response of the molecular clock is controlled independently of the timing of PDF release.
The "molecular clock" is not strictly clock-like, however it is regular enough that substitutions do relate to time.
The molecular clock is the rate at which mutations, and any resulting evolutionary changes, occur in a given species.
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The molecular clock was also used to compute the date of duplication by calculating the number of substitutions per silent site (Ks).
The molecular clock was not rejected in any case.
The molecular clock was rejected for very few datasets (Table 1).
Both positive and negative loops of the molecular clock are involved in cell cycle control.
A global molecular clock was rejected in favor of lineage-specific rates of molecular evolution (LRT: unconstrained model –ln L = 14940.81; constrained model –ln L = 15209.60; χ288 = 537.58; p<0.001).
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