Sentence examples for molecular clock due from inspiring English sources
Amino acid sequence comparisons for a specific protein can only be used as a molecular clock due to mutations in the gene coding for that protein.
We attempted neither to produce a phylogeny of Hymenoptera using the mtDNAs sequences, nor did we try to use a molecular clock due to very limited taxon sampling.
Unequal branch lengths can be either caused by unequal evolution rates across lineages within the study group (i.e. relaxation of the molecular clock assumption), or due to an asymmetrical topology, which can arise as a result of differential speciation or extinction rates and/or incomplete taxon sampling [ 6].
Precise estimation of the age of separation using a molecular clock approach is difficult due to the lack of reliable calibration points.
Taken together, these data indicate that the circadian behavioural abnormalities seen in Aβ-expressing flies are not caused by loss of central molecular clock function but are more likely due to damage in the downstream pathways in the clock neurons or other distal brain region.
One has to keep in mind that this molecular clock analysis might be under- or overestimated due to mutational masking and substitutional saturation.
Future studies should explore how molecular clock models that account for rate variation due to life history traits could be implemented.
These results are consistent with the molecular clock being constant mainly over longer evolutionary times due to cancellation of low and high rates of evolution and suggest that observations of neutrality may be overestimated due to such averaging effects.
This is most likely due to the calibration of the molecular clock of the different DNA stretches of the mitochondrial genome, which need further fine-tuning.
The wide range of dates is due to the different records used to calibrate the molecular clock.
Molecular clock analysis revealed that the exponential increase of the Ne was not due to an increased evolutionary or replication rate of HIV-1 in tissues with different histopathology.
