Sentence examples for molecular clock assumption from inspiring English sources

Many of these criticisms have become less relevant, however, with recent developments in phylogenetic dating methods that permit relaxing the molecular clock assumption, i.e., allowing rate heterogeneity across lineages (e.g., Drummond and Rambaut 2007), or incorporating the uncertainty in the fossil calibration through the use of probabilistic approaches (Ho 2007).

The program baseml was employed to analyze a molecular clock assumption.

The absence of such heterogeneity permitted the molecular clock assumption to be applied to date the time of transfer of these numts into the nuclear genome.

Because the likelihood ratio test failed to reject the molecular clock assumption for the two groups of sequences, the program mcmctree of PAML 4.1 [65] was used to estimate divergence times.

Likewise, the posterior distribution of the coefficient of variation estimated here strongly renders a global molecular clock assumption untenable, and the calculated covariance among inferred branch rates suggest there is little evidence for an ancestor-descendant autocorrelation of rates in the phylogeny used in this study.

For instance, with the k-means clustering algorithm, the estimated dates for the hominoid divergence (node 59 in Table 1) vary from 13.5 million years (MY) to 13 MY when the number of local clocks k is varied from one, which is the molecular clock assumption, to six.

A probabilistic calibration prior was used, which is favorable for dating in combination with relaxed molecular clock assumptions (39 ).

This test compares the log-likelihood of the ML trees under alternative molecular clock assumptions (i.e. a relaxed vs. an enforced molecular clock).

Three of the trees (AA, BB and AB) satisfied the molecular clock assumptions, while three trees (CC, DD and CD) did not.

One possible explanation for this is that CYTB is known to violate molecular clock assumptions (Nabholz et al., 2008) and we make this assumption in calculating phenotype parameter values and branch lengths.

Under a molecular clock or near-molecular clock assumption, we can expect pairs of genes having started diverging later to have accumulated fewer changes, and therefore to have generally higher alignment score, which motivates the use of BBH (fig. 1 a).